Dr. Martin Haubrock
Groupleader: Gene Regulation
Telephone: 0551-3961784
E-Mail: martin.haubrock@bioinf.med.uni-goettingen.de
Location: Goldschmidtstr. 1, 37077 Göttingen,
2. OG, Room: 2.111
Curriculum Vitae
| 2021: PhD: Prediction, analysis and significance of characteristic transcription factor binding sites and their potential master control function for the transcriptional gene regulation |
| since 10.2018: Research assistant and group leader (Group Gene Regulation) at the Institute of Medical Bioinformatics (Head: Prof. Beißbarth) , University Medical Center Göttingen |
| 01.2003-09.2018 Research assistant and lecturer at the Institute of Bioinformatics (Head: Prof. Wingender), University Medical Center Göttingen |
| 06.2000/12.2002 Research and development at Biobase GmbH (Braunschweig/Wolfenbüttel) |
| 02.2000: Diplom (Masters) Thesis: PathFinder: reconstruction and dynamic visualization of metabolic pathways. |
| 1994-2000: Study of Computer Science and Bioinformatics (Faculty of Technology) at the University of Bielefeld |
| 1987-1990: Beisenkamp Gymnasium - Hamm (Westf.), Germany |
| 1981-1987: Realschule Bönen (Secundary School), Germany |
| Feb. 8, 1971: Born in Unna (Westf.), Germany |
Research focus
Analysis and interpretation of gene regulation in eukaryotes
- Prediction of TFBSs
- Prediction and analysis of transcriptional networks
- Modeling of gene regulatory networks
- Analysis of DNA hypersensitivity assays, immunoprecipitation (IP) of proteins that interact with DNA, modified histones, chromatin remodelling proteins and transcription factors sequencing data
- Application of machine learning methods to analyze nucleosome positioning, transcription factor binding sites composition in the context of proximal and distal regulatory interactions
Publications
Selected Publications
Daou R, Beißbarth T, Wingender E, Gültas M, Haubrock M.:
Constructing temporal regulatory cascades in the context of development and cell differentiation.
PLoS One. 2020 Apr 10;15(4):e0231326. doi: 10.1371/journal.pone.0231326.
Wingender E., Schoeps T., Haubrock M., Dönitz J.:
TFClass: expanding the classification of human transcription factors to their mammalian orthologs.
Nucleic Acids Res. 2018 Jan. 4;46(D1):D343-D347 doi: 10.1093/nar/gkx987
Haubrock M., Hartmann F., Wingender E.:
NF-Y binding Site Architecture Defines a C-Fos targeted Promoter Class.
PLoS One. 2016 Aug. 12; 11(8):e0160803 doi: 10.1371/journal.pone.0160803
Schirmer M.A., Lüske C.M., Roppel S., Schaudinn A., Zimmer C., Pflüger R., Haubrock M., Rapp J., Güngör C., Bockhorn M., Hackert T., Hank T., Stroebel O., Werner J., Izbicki J.R., Johnsen S.A., Gaedecke J., Brockmöller J., Ghadimi B.M.:
Relevance of Sp Binding Site Polymorphism in WWOX for Treatment Outcome in Pancreatic Cancer.
J. Natl. Cancer Inst. 2016 Feb. 8; 108(5) doi: 10.1093/jnci/djv387